Dry eye is a complex disease where all different components of the ocular surface develop complex interactions leading to impaired regulatory and defense mechanisms. Hyperosmotic stress, inflammation, neurogenic stimulation, tissue damage are interdependent in a self-stimulated way, together with extraocular influence of the immune system, the trigeminal pathway and probably the microbiome. The objectives of this webinar are to share recent knowledge on these complex mechanisms, to emphasize the role of chronic inflammation in the development of dry eye, to inform the audience on current research on disease biomarkers, both on clinical and biological sides, and give an overview on anti-inflammatory strategies, susceptible of helping ophthalmologists to alleviate symptoms and patient to get out of the vicious cycles of dry eye disease.
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